As illustrated in Brodmann-10, It constitutes most of the orbital gyri, gyrus rectus and the most rostral portion of the superior frontal gyrus.
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Meta-analyses of neuroimaging studies in major depression reported that, compared to controls, depressed patients had increased volume of the lateral ventricles and adrenal gland and smaller volumes of the basal ganglia, thalamus, hippocampus, and frontal lobe ( including the orbitofrontal cortex and gyrus rectus ).
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